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However, in our study, we found that the risk for cardiovascular events (including coronary artery disease, angina pectoris, unstable angina, myocardial infarction, atrial fibrillation, bradycardia, palpitations and tachycardia) with combination therapy was similar to that with monotherapies, and in the subgroup analysis, the risk for genital infection was higher when an SGLT-2i was added to GLP-1RA monotherapy
This regulatory gap is the core problem for interaction assessment
Rather than physically removing or heating tissue, these approaches aim to restore the biochemical environment that supports natural collagen and elastin production
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