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This multi-receptor approach is designed to produce greater weight reduction than dual or single agonists, as demonstrated in the 2023 phase 2 trial data
ShamsherEKhanRSDavisBMDineKLuongVSomavarapuSet al
In vivo BBB Permeability Measurements To assess in vivo permeabilization of the BBB in the AOM mouse model of HE, a modified Evans blue dye assay was performed in vehicle and AOM mice
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