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Metabolite extraction followed the protocol described by Huang et al

Patients with diabetic retinopathy should report any vision changes, as rapid improvement in blood glucose can temporarily worsen retinopathy, particularly with semaglutide

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The cell pellet was resuspended and incubated for 30 min on ice with 25 L of staining mix in PBS containing 0.04% BSA, TruStain FcX Block (BioLegend 101320), and the mouse cell surface protein antibody panel containing the following oligo-conjugated anti-mouse antibodies (TotalSeq-A BioLegend) diluted 1:500: CD23 (Cat