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Peak dopaminergic activation hits 2 to 6 hours after the dose
Site rotation prevents local tissue irritation from repeated injections
To establish a connection with the NO-system, l-NAME (5 mg/kg intraperitoneally) (worsening) and/or L-arginine (100 mg/kg intraperitoneally) (beneficial effect) were given alone or together
It is not found in nature in its isolated form but is derived from a larger protective protein present in gastric secretions
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