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The safe early-dosing window: 24 hours, not 48 The consensus clinical guidance, based on the pharmacokinetic data above, is: Safe: Up to 24 hours early (dosing on day 6 instead of day 7)
Instead, discuss implementing a bone health protection plan alongside your treatment
If nausea or gastrointestinal issues are still significant after four full weeks, staying at the current dose longer is often better than escalating
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