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A randomized, double-blind, placebo-controlled study of an oral, extended-release formulation of phentermine/topiramate for the treatment of obstructive sleep apnoea in obese adults
This decline contributes to fatigue, slower cellular repair, and reduced metabolic flexibility
The potential for these agents to disrupt sleep-wake stability through modulation of orexin signaling and REM architecture warrants further mechanistic investigation in future studies
Common Complaints and Friction Points Upfront multi-month billing before clinician review is a recurring source of confusion or dissatisfaction
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