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Moreover, elevated GSH levels can protect tumor cells by reducing the cytotoxic effects of several chemotherapy drugs, including cisplatin, doxorubicin, melphalan, and paclitaxel, ultimately leading to drug resistance [17]
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Furthermore, validation of the assay demonstrated linearity, as well as recoveries, of within 15% of expected values spanning the assays range, demonstrating the effectiveness of the SDS protocol to disrupt the IGF-1/IGFBP complex
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