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Users often report improved stamina, reduced fatigue, and better physical performance, though these subjective reports have not been validated in controlled human trials
in Cell Metabolism note that SIRT1 activation improves mitochondrial efficiency and promotes a shift toward lipid utilization for energy, which can be especially beneficial in endurance and fat-loss settings (Price et al., Cell Metabolism )
The animal data suggest lean mass is preserved, but human body composition data is lacking
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