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For example, ROS-responsive nanoparticles self-assembled from a hybrid platinum prodrug CPT-Pt (IV), ROS-sensitive polymer, and mPEG2k-DSPE can accumulate at tumor sites and release cisplatin and CPT, leading to DNA double-strand damage, ultimately activating the cGAS-STING pathway, inducing DCs maturation and increasing tumor infiltration of CD8 + T cells (230)

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The harsh acids in your stomach and the enzymes in your gut are very good at breaking down proteins

Small moleculeinduced ferroptosis strongly inhibits tumor growth and may be a promising therapeutic modulator for enhancing the sensitivity of chemotherapeutic drugs, especially as drug resistance is emerging (Lu B