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PLoS ONE 11:e0148827 Zhang L, Zhang L, Li L, Holscher C (2018) Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinsons disease mouse model

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For people wondering about the immediate effects, this article on whether semaglutide works right away explains the realistic onset timeline, and this piece on immediate appetite suppression addresses one of the most common questions new users ask

Both routes share systemic adverse event profiles that are compound-specific rather than route-specific