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Zepbound achieved massive commercial success in 2025, with estimated full-year sales reaching approximately $13.5 billion , representing a near-tripling (+175%) of revenue compared to the prior year
For most patients, these symptoms are temporary and manageable, but anything persistent or severe - such as abdominal pain, bladder issues, or constant insomnia - warrants medical review
It can result in various side effects and complications
However, high doses ( 0.5 mg/kg/d) may activate the SREBP-1c pathway, increase liver fat synthesis, and lead to hypertriglyceridemia and fatty liver
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