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A further repeating design principle is amphipathicity, which refers to the presence of both hydrophobic and hydrophilic sides
Acta Mol
In Biermers disease, two prospective controlled randomized studies, a recent systematic review by the Cochrane group and four prospective studies were found and provide evidence that oral vitamin B12 treatment may adequately treat cobalamin deficiency
For some, the effects may be subtle at first or become noticeable only after repeat doses
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