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On the basis of liraglutide, semaglutide replace Lys with Arg at 34 position, replace Ala with 2-aminoisobutyric acid (AIB) at 8 position, and conjugate Lys with 18 carbon fatty acid chain at 18 position

Additionally, by reducing weight, many users experience improvements in other obesity-related conditions, such as sleep apnea, hypertension, and high cholesterol levels

It is not FDA-approved for human use, is not a legal dietary supplement ingredient in the United States, and is not sold by FormBlends

In the STEP 5 study, participants taking semaglutide lost an average of 15.2% of their body weight over two years, compared with 2.6% in the placebo group