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Particularly noteworthy was the robust association observed with gout
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Watson typically starts patients on liraglutide, which tends to be the gentlest and least expensive of the GLP-1s
However, SGLT2-i could reduce renal and extra-renal glucotoxicity by inhibiting many pro-inflammatory pathways such as low serum ketone levels, hyperuricemia, oxidative stress and advanced glycation-end products (AGEs) induced by hyperglycemia (33)
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