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Previous Weight Loss Attempts If youve tried other medications without success, semaglutide might be a good next step

For example, prioritize vegetables, fruits, whole grains, and legumes

Orforglipron also demonstrated superiority over oral semaglutide (Rybelsus) in a head-to-head trial for blood sugar control and weight loss in type 2 diabetes, delivering better results with fewer food and water intake restrictions