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The important thing to remember about these two is that one is a brand name for semaglutide that is prescribed for weight loss (Wegovy ), and the other is the active ingredient in two branded medications, Zepbound and Mounjaro (tirzepatide)
Of particular interest for weight loss are GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptor agonists
The speed at which tirzepatide works and the magnitude of weight loss, averaging 20-22% of body weight in trials, set a high bar for alternatives
Contrave and Wegovy both carry a boxed warning, the FDAs most serious safety warning
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