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Approximately five of the original 19 peptides are expected to remain on the restricted list likely those with more limited safety profiles, higher misuse potential, or closer proximity to existing FDA-approved drug categories
In some cases, clinicians may choose this approach when rapid therapeutic benefit is needed, but it is always paired with careful monitoring because the risk of GI events is higher with faster dose increments
Derosa G, Maffioli P, Salvadeo SA, Ferrari I, Ragonesi PD, Querci F, et al
Despite that the serious adverse events (SAE) were similar to semaglutide 1 mg, the AE leading to drug discontinuation were 1030% compared to 4% with semaglutide 1 mg (Table 3)
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