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This doesn't mean it's unsafe it means it hasn't gone through the specific regulatory pathway the FDA requires for approved drugs

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Side effects of injectable B12 may include such gastrointestinal symptoms as nausea, vomiting, mild diarrhea, headache and dizziness, skin rash, and itching (presumably, related to skin rash)

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Studies have identified significant reductions in testosterone levels in males over the past few decades, independent of age

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