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23 In clinical trials, treatment-discontinuation rates are around 5% to 10%

Systematic reviews of studies conducted in perioperative patients taking GLP-1 agonists found larger volumes of solid food in the stomach even after adequate fasting preoperatively and a higher rate of (post operative nausea and vomiting.7,8 The ASA also recommend withholding GPL-1 agonists preoperatively.9 Emergency clinicians should treat these patients as higher risk during procedural sedation or intubation and prepare accordingly

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