Lund A, Knop FK, Vilsbll T: Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes: differences and similarities
Tirzepatide (Mounjaro, Zepbound) works through a dual mechanism as both a GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist
Clinical trials show Wegovy produces an average of around 15% body weight loss, roughly double what patients typically see with Qsymia
Allen M, Huang B, Notaras M, Lodhi A, Barrio-Alonso E, Lituma PJ, Wolujewicz P, Witztum J, Longo F, Chen M, Greening DW, Klann E, Ross ME, Liston C, Colak D (2022) Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling