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Case 1: A 10 months old girl with high-density lipoprotein cholesterol (HDL-c) 35mg/dl and triglycerides 227mg/dl
The primary preclinical evidence comes from mouse studies showing reduced body weight and adipose mass in diet-induced obese mice (2018), improved grip strength in aged mice (2024), and beneficial microbiome changes when combined with caloric restriction (2022)
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point towards the positive effect of B12 on GSH redox capacity as a possible mechanism of action 28 that may improve brain function as well as the immune system and the gastrointestinal tract in individuals with ASD
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