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Biochem Soc Trans 2014

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Gastroparesis is a condition that makes a persons stomach contents take longer to move down the intestinal tract, which may cause vomiting, diarrhea, and other complications

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So adjunctive therapies are supposed to be therapies that help insulin with glucose-lowering. The history of adjunctive therapies in type 1 diabetes began with metformin, an oral medication approved in the U.S