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Tobacco smoking causes secondary polycythemia and a mild leukocytosis among heavy smokers in Taif City in Saudi Arabia
Consistent with this, the GLS inhibitor telaglenastat (CB-839) has entered phase I/II combination studies with immune checkpoint inhibitors such as nivolumab, reflecting a typical translational closed loop of amino acid metabolism-targeted drugcombination immunotherapyclinical safety and efficacy signal evaluation (119)
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a new therapeutic direction in host defence
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