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Such sustained weight loss of this magnitude is infrequently observed in clinical trials of other weight-loss interventions, Michelle Routhenstein, RD, CDN, a preventive cardiology dietitian at EntirelyNourished.com who was not involved in the study, told Medical News Today
A: While skin hydration is immediate, most users notice visibly smoother and more toned-looking skin within 23 weeks of consistent, twice-daily use
Mathieu C, Rodbard HW, Cariou B, et al
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