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NAIONs pathophysiology remains incompletely understood but involves vascular dysregulation, possibly exacerbated by drug-induced sympathetic nervous system changes and optic nerve head vulnerabilities such as a smaller Bruchs membrane opening
Digestive Issues: Nausea, bloating, or diarrhea (rare)
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Due to the higher availability of L-carnitine, CAR may have an adequate flux of L-carnitine and acylcarnitine in PBMC during LPS-induced inflammation and may not need to adapt by upregulating SLC25A20 in PBMC
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