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Campione et al 20 found that enzyme glutathione-s-transferase-pi (GST-pi), present in keratinocytes and melanocytes, protects cells against tumor progressionnotably, sun exposure-associated melanoma cells
Editing efficiency was determined on bulk-edited cell populations by targeted PCR of the Cas9-targeted region and secondary PCR using overhang sequences (Table S1), followed by Illumina MiSeq, as previously described (Aubrey et al, 2015)
Support for Mitochondrial Energy Production : Through its influence on lipid metabolism, AOD-9604 indirectly enhances mitochondrial ATP generation by increasing the availability of fatty acids as substrates for oxidation
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