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Additionally, exposure of erythrocytes to heavy metals, pollutants, and xenobiotics triggers eryptosis through various mechanisms of cell death
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It carries an arginine substitution at position 3 and a 13-amino-acid N-terminal extension, giving it 83 amino acids total versus 70 for native IGF-1
Since glutathione is the major antioxidant in brain, modulation of its biosynthesis by withanolide A under hypoxic condition could ameliorate oxidative stress induced neurodegeneration and consequent memory dysfunction
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