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In pre-clinical and clinical research models, ARA-290 has demonstrated significant activity across multiple domains: Neuropathy and Pain Research: Diabetic peripheral neuropathy (DPN) Phase 2 clinical study confirmed ARA-290 significantly improved HbA1c, lipid profiles, and neuropathic symptom scores in type 2 diabetes patients over 56 days

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The CagriSema combination may follow a parallel but distinct regulatory pathway, potentially offering an alternative to monotherapy approaches depending on comparative efficacy and safety data

Nutrients, 14 (9), 1727