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Both native GLP-1 and GLP-1RA exert multiple actions in the cardiovascular system, including reduction of blood pressure in hypertensive individuals, inhibition of postprandial chylomicron secretion, attenuation of inflammation in the heart and blood vessels, and reduction of ischaemic cardiac injury, but also increases in heart rate (Fig
Precautions: Before using Rybelsus, inform your doctor if you have any pancreas or stomach problems, severe dehydration, or a history of diabetic ketoacidosis
Patients should attend scheduled visits for blood pressure checks, metabolic panel assessments (including renal function and electrolytes), and evaluation of diabetes control through hemoglobin A1c testing
Keep semaglutide refrigerated at a temperature between 36F and 46F (2C to 8C)
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