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For example, WJ460 inhibits the oncoprotein myoferlin, triggering mitophagy and ROS accumulation while reducing both SLC7A11 and GPX4 expression [69]

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The pooled fractions (approximate 6 ml) were concentrated (approximate 0.6 ml) (centrifugal tube: Amicon Ultra-4 centrifugal filter unit with 10 kDa cutoff, from Millipore) and followed by 2D crystallization trials

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