ishin glutathione before and after Glutathione: How This Antioxidant Affects Skin, Aging ISHIN PREMIUM REVIEW | 3

Preparation of working reagents KH 2 PO 4 (0.2 M) and Na 2 PO 4 (0.2 M) were mixed at a ratio of 40.5:9.5, (v/v), and the pH, if necessary, was adjusted to 7.4 by adding KH 2 PO 4 or Na 2 HPO 4 solutions drop-wise

It inhibits NNMT (nicotinamide N-methyltransferase), an enzyme regulating metabolism, fat storage, and NAD+ consumption.[4][27][6] NNMT methylates nicotinamide, a NAD+ breakdown product, diverting it from recycling and reducing available NAD+

What this all means is that the water molecules that are produced by glutathione reductase will be deupleted

If that doesn't help, copper peptides may not be ideal for your skin type