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Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation

While the goal is to treat patients before the development of acute liver failure, treatment should still be given to patients who are found to be in active hepatic failure since NAC appears to improve hepatic perfusion and oxygen delivery, to refine mitochondrial energy metabolism, and to facilitate scavenging of reactive oxygen and nitrogen species

At low doses (13 g/kg/min) , dopamine primarily stimulates D receptors , producing localized renal and visceral vasodilation with little effect on systolic blood pressure (SBP) and heart rate (HR), while diastolic blood pressure (DBP) and systemic vascular resistance (SVR) may remain unchanged or decrease slightly

Physiological review