tirzepatide for fatty liver Eli Lilly says weight loss drug shows promise as treatment disease – NBC 6 South Florida Does Tirzepatide Help Fatty Liver?

B., Aroda, V

Heres what I found: Bariatric surgery leads to greater, more durable weight loss and comorbidity reduction compared to GLP-1s GLP-1s offer substantial but less sustained comorbidity benefit with higher discontinuation rates (up to 50% at 35 yrs) GLP-1s do not eliminate the need for bariatric surgery in severe obesity Total weight loss trends higher for bariatric surgery, and real-world GLP-1 effectiveness is generally lower than clinical trial results (a significant finding that deserves its own post) Bariatric surgery is generally more effective than GLP-1s for long-term diabetes remission and cardiovascular risk reduction GLP-1s are associated with higher ongoing costs and are less cost-effective than bariatric surgery long-term The take home: GLP-1s are a valuable addition but dont replace bariatric procedures for patients with severe obesity or those requiring durable, substantial weight loss with co-morbidity reduction

Doctors prescribe this amount because its based on clinical testing done by the drug manufacturers, ensuring the dose is both effective and safe for most patients

Endocr Rev 37(5):521547)