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Ongoing research is needed to assess potential risks associated with prolonged use, including cardiovascular effects and the development of pancreatitis or pancreatic cancer

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References Barisic I, Balenovic D, Klicek R, Radic B, Nikitovic B, Drmic D, Udovicic M, Strinic D, Bardak D, Berkopic L, Djuzel V (2013) Mortal hyperkalemia disturbances in rats are NO-system related