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COL3A1 testing identified the Glu682Lys variant (identical pathogenic variant to family 1 and family 4), which was subsequently identified in the father (IV.1) and another daughter (V.3)
Recent studies have shown that reactive oxygen species (ROS) are involved in the molecular mechanisms of breast cancer occurrence and development [7,8,9]
When used in combination with other medical treatments, melatonin has been shown to enhance the overall effectiveness of melasma therapies by reducing oxidative stress and inhibiting melanin production
