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In the heart, histamine increases the force of contraction, and even as far back as 1913, histamine has been known to induce heart arrhythmias.[ref][ref] Mast cells and histamine release: Mast cells are a type of immune cell that creates and stores histamine
Interestingly, dapagliflozin may bind with FPN1 to regulate the ubiquitination and degradation of FPN1 [244]
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