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As oral GLP-1s are going to expand access to the drugs, gaining an understanding of these mechanisms is especially relevant, they added
Keloid Senescent Fibroblast Elimination & SASP Suppression (Communications Biology, 2025) FOXO4-DRI Induces p53-pS15 Nuclear Exclusion and Apoptosis in Keloid Fibroblast Models A study published in Communications Biology (Nature Publishing Group, 2025) used single-cell RNA sequencing to characterise the senescent cell landscape in keloids pathological scars with tumour-like aggressiveness
Cell culture and transfection Gastric cancer cell lines SNU638 (KCLB No.00638), SNU216 (KCLB No.00216), and SNU668 (KCLB No.00668) cells were obtained from KCLB (Korean Cell Line Bank), and HEK293T (CRL-3216) cells were obtained from ATCC (American Type Culture Collection)
Banerjee, G
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