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Unclear long-term safety: There is limited data on chronic use or systemic effects
GLP-1 (glucagon-like peptide-1) agonists function by mimicking the naturally-occurring hormone glucagon, which helps regulate insulin release and digestion
Because of the risk of addiction or abuse, such stimulant drugs are "controlled substances," which means they need a special type of prescription
Although the peptide library was constructed from a single mRNA library, the cyclic scaffold ensured that the D-library (whose members contain a single D Y at the N-terminus and other elongating amino acids are L-form) and the L-library (comprising all L-amino acids with L Y at the N-terminus) covered different three-dimensional spaces
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