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Disruption of GH and IGF1 signaling extends lifespan, enhances insulin sensitivity, decreases DNA and protein oxidation in the liver, reduces cancer incidence and may reduce age-related inflammation
Its FDA approval specifically for weight loss in 2021 opened the floodgates for prescriptions to people without diabetes, a population that the studies suggest may face even higher risks for certain complications like NAION
It involves administering a moderate dose daily for a short period before tapering down to a less frequent maintenance schedule
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