Disruption of this process, known as ER stress, is associated with many disease states, including obesity and its comorbidities (Mohan, R, Brown, Ayyappan, & G, 2019)
Not for Human Consumption.
no AEs Propranolol - side effects: drowsiness, sleep disturbance, weight gain, fatigue, dry mouth Side Effects of Beta-Blockers (Medical Letter Jan 2012)Fatigue, depression, bradycardia, erecticle dysfunction, decreased exercise tolerance, heart failure, worsening of peripheral aterial insufficiency, may aggravate allergic reactions, bronchospasm, may mask symptoms of and delay recovery from hypoglycemia, Ranaud's phenomenon, insomnia, vivid dreams or hallucinations, acute mental disorder, increased serum triglycerides, decreased HDL cholsterol, increased incidence of diabetes, sudden withdrawal may lead to exacerbation of antina and mycoardial infarction New Daily Persistent Headache (NDPH) Rapid development (over less than 3 days) of an unrelenting headache
Search for novel steps and molecules that could be therapeutically targeted should be prioritized to translate scientific discoveries in the field from bench to bedside