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melanin production to make the skin brighter and free from dark spots and post-inflammatory pigmentation
It is the first membrane-permeable, selective inhibitor of nicotinamide N-methyltransferase (NNMT), developed at the University of Texas in 2017
However, it is known that through dietary intake and/or supplementation, antioxidants such as vitamin C, E, and carotenoids are deposited into the epidermis at higher concentrations compared with the dermis [4,5,6], which suggests the importance of inside to outside treatment of the skin
2020a, b), adding to its credit in treating inflammatory diseases such as arthritis, colitis, and neuroinflammation
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