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The medications do most of the work
Cancer Invest 25:117123
Lipoic acid might be able to increase glutathione synthesis in aged rats by up-regulating the expression of -glutamylcysteine ligase (-GCL), the rate-limiting enzyme in glutathione synthesis (31), and by increasing cellular uptake of cysteine, an amino acid required for glutathione synthesis (32)
However, its potential impact on glucose metabolism necessitates careful consideration for individuals with diabetes or those at risk of elevated blood sugar levels
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