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Who Can Take GLP-1 Medications
Accessed 3 Sep 2021 Mendiola AS, Cardona AE (2018) The IL-1 phenomena in neuroinflammatory diseases
As weight decreases, patients typically experience: Reduced joint pain and improved mobility Potential improvements in sleep quality and sleep-disordered breathing (though semaglutide is not FDA-approved to treat sleep apnea) Possible improvements in cardiovascular function and stamina as a result of weight reduction Enhanced ability to engage in physical activity Additionally, improved self-efficacy and mood can contribute to perceived energy increases
GLP-1 receptor agonists are licensed in the UK for type 2 diabetes and weight management, including semaglutide, dulaglutide, and liraglutide These medications reduce HbA1c by approximately 1.01.5 percentage points and improve both fasting and post-meal glucose levels Weight loss associated with GLP-1 therapy can lead to secondary improvements in insulin resistance, particularly through reduction of visceral fat Common side effects include gastrointestinal symptoms such as nausea, vomiting, and diarrhoea, which typically diminish over several weeks NICE recommends continuation only if patients achieve at least 1.0 percentage point HbA1c reduction within six months of treatment initiation Patients with diabetic retinopathy require close monitoring, and GLP-1 medications should be discontinued at least two months before planned pregnancy Table of Contents What Are GLP-1 Receptor Agonists and How Do They Work
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