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In 2015, the EFSA released B12 recommendations that considers the research published since the 1998 IOMs recommendations (EFSA, 2015
Cyanocobalamin or methylcobalamin (B12): Occasionally causes injection site discomfort and redness
However, this study examined only the effects of lipotropic substances in the rats diet, not lipotropic injections, and has limitations as an animal study
2Slowly inject the water down the inside wall of the vial, avoiding foaming
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