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Discussion To our knowledge, this is the first real-world-study-based CEA of using GLP-1RAs versus insulin for T2D patients who require a greater glucose-lowering effect of injection therapy, and the first systematic review on this topic
For this secondary report, we estimated that the study would have at least 80% power to detect differences between groups in physical functional performance (0.8 s in the stair climb test), cardiorespiratory fitness (3.0 mL/min/kg FFM), and muscle strength (15 Nm)
Mounjaro (Tirzepatide) is typically recommended for individuals who are obese or overweight, especially those with related health conditions such as type 2 diabetes , high blood pressure, or high cholesterol
Allergic reactions are extremely rare but could manifest as rash, swelling, or difficulty breathing if any such signs occur, seek immediate medical help
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