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55 In esophageal squamous cell carcinoma (ESCC), QSOX2 promotes disulfide bond formation in TSC2, enhancing its phosphorylation by Akt and activating the mTOR/4E-BP1/c-Myc axis, thereby upregulating CSC markers (e.g., CD44, Notch1) and promoting platinum resistance
Consult with a qualified healthcare provider before starting any supplementation or hormone therapy program
Luszczek, Research Specialist at the Research Core Facility at Louisiana State University Health Sciences Center in Shreveport for their expert technical assistance
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