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Sikiric P, Seiwerth S, Grabarevic Z, Petek M, Rucman R, Turkovic B, et al
The hormone glucagon, which is produced by alpha cells in the pancreas, partners with insulin to regulate blood glucose levels
Given the 5 to 8 minute plasma half-life, protocols that use subcutaneous injection are working against basic pharmacokinetics
They act on different appetite pathways cagrilintide is a long-acting amylin analog, while tirzepatide is a dual GIP/GLP-1 receptor agonist which is the theoretical reason researchers discuss pairing them
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