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And the early growth response 1 (egr-1) gene expression pattern, originally identified in skin wound healing, also appears in muscle and tendon repair work, suggesting a shared transcriptional response

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Docking substrates into the active site of the mutant Asn240Lys suffered from steric and entropic problems as Lys at position 240 oscillates (as evidenced by docking showing a wide range of different Lys240 positions), thereby obstructing access to the active site