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IGF-1 therapy relieves hepatocyte premature senescence via inhibiting nuclear p53progerin interaction To further reveal the role of IGF-1 in oxidative stress-induced premature aging of hepatocytes, firstly, we explored whether short-term or prolonged exogenous IGF-1 treatment attenuated hepatocyte premature aging
In the study, people with obesity or those who were overweight and also had at least one comorbidity (such as high blood pressure, type 2 diabetes, or lipid disorders) took Wegovy for 68 weeks
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