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While usually well-tolerated, Semaglutide can cause common side effects, including nausea, vomiting, diarrhea, and constipation, especially during the initial weeks of treatment
People who are very lean in the abdominal area, particularly men with low body fat percentages, may find this site less comfortable and should consider the thigh as their primary site instead
Fertility may improve unexpectedly while taking GLP-1s, so reliable contraception is important if pregnancy is not yet the goal
In some cases, it may even lead to suicidal thoughts
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